(Q21126609)

LDL receptor-like superfamily

1 reference

peptidase S1A, matriptase-2

1 reference

Peptidase S1, PA clan

1 reference

SEA domain superfamily

1 reference

CUB domain, protein family

1 reference

SEA domain, protein family

1 reference

Serine proteases, trypsin domain, protein family

1 reference

Serine proteases, trypsin family, histidine active site, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A repeat, protein family

1 reference

Serine proteases, trypsin family, serine active site, protein family

1 reference

serine-type peptidase activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

metalloendopeptidase activity

IEA

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

serine-type endopeptidase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

intracellular anatomical structure

IEA

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

27 March 2018

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

integral component of membrane

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

membrane protein proteolysis

IEA

biological process

1 reference

8 April 2019

Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

intracellular signal transduction

IMP

1 reference

1 January 2018

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

1 January 2018

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

27 March 2018

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IU80&geneProductId=UniProtKB:Q8IU80

negative regulation of BMP signaling pathway

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 reference

8 April 2019

Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

extracellular matrix organization

IMP

1 reference

1 January 2018

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

negative regulation of transcription, DNA-templated

NAS

1 reference

8 April 2019

Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

1 January 2018

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

extracellular matrix disassembly

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

collagen catabolic process

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

3 references

8 April 2019

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

2 references

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IU80

Serine proteases, trypsin family, serine active site

IBA

has part(s)

1 reference

CUB domain

1 reference

low-density lipoprotein (LDL) receptor class A repeat

1 reference

serine proteases, trypsin domain

1 reference

serine proteases, trypsin family, histidine active site

1 reference

SEA domain

1 reference