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(Q21127068)
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Ring finger protein 182
mammalian protein found in Homo sapiens
RNF182
RING-type E3 ubiquitin transferase RNF182
RING finger protein 182
E3 ubiquitin-protein ligase RNF182
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N6D2
part of
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N6D2
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger, RING-type, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N6D2
encoded by
RNF182
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N6D2
molecular function
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IPI
retrieved
8 April 2019
stated in
The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IPI
retrieved
8 April 2019
stated in
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IPI
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
ubiquitin-protein transferase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IDA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
cell component
cytoplasm
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
retrieved
8 April 2019
stated in
A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IDA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
biological process
protein ubiquitination
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IEA
retrieved
8 April 2019
stated in
A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation
GOA
curator
UniProt
UniProt protein ID
Q8N6D2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N6D2
determination method
IDA
has part(s)
Zinc finger, RING-type, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N6D2
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8N6D2
Identifiers
RefSeq protein ID
NP_001158504
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
221687
NP_001158505
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
221687
NP_001158506
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
221687
NP_689950
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
221687
XP_016865939
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
221687
UniProt protein ID
Q8N6D2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8N6D2
Ensembl protein ID
ENSP00000420465
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000420465
ENSP00000441271
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000441271
ENSP00000442021
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000442021
ENSP00000443228
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000443228
ENSP00000417500
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000417500
ENSP00000417514
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000417514
ENSP00000418717
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000418717
ENSP00000419329
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000419329
Sitelinks
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