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Somatostatin receptor 4
mammalian protein found in Homo sapiens
G-protein coupled receptor
SSTR4
somatostatin receptor type 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P31391
part of
Somatostatin receptor 4
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P31391
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P31391
encoded by
SSTR4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P31391
molecular function
neuropeptide binding
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
G protein-coupled receptor activity
determination method
IEA
2 references
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IEA
signal transducer activity
determination method
IEA
1 reference
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IEA
somatostatin receptor activity
determination method
IBA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
G protein-coupled receptor activity
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
peptide binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
integral component of membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
neuron projection
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IBA
plasma membrane
determination method
TAS
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
integral component of plasma membrane
determination method
TAS
1 reference
retrieved
16 July 2018
stated in
Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
TAS
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
integral component of plasma membrane
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
biological process
G protein-coupled receptor signaling pathway
determination method
TAS
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
retrieved
8 April 2019
stated in
C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
forebrain development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
cellular response to glucocorticoid stimulus
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
cell migration
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
arachidonic acid metabolic process
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IEA
positive regulation of MAPK cascade
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IEA
negative regulation of cell population proliferation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
TAS
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31391
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
somatostatin signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
chemical synaptic transmission
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31391&geneProductId=UniProtKB:P31391
determination method
IBA
positive regulation of ERK1 and ERK2 cascade
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
positive regulation of arachidonic acid secretion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IEA
neuropeptide signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31391
determination method
IBA
physically interacts with
somatostatin
object has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1823872
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P31391
Identifiers
RefSeq protein ID
NP_001043
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6754
UniProt protein ID
P31391
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P31391
Ensembl protein ID
ENSP00000255008
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000255008
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