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Transmembrane channel like 2
mammalian protein found in Homo sapiens
transmembrane cochlear-expressed gene 2
transmembrane cochlear-expressed protein 2
transmembrane channel-like protein 2
TMC2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDI7
part of
Transmembrane channel-like protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8TDI7
TMC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDI7
encoded by
TMC2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDI7
molecular function
voltage-gated calcium channel activity
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDI7&geneProductId=UniProtKB:Q8TDI7
determination method
IEA
mechanosensitive ion channel activity
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDI7&geneProductId=UniProtKB:Q8TDI7
determination method
IEA
molecular function
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
ND
ion channel activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IBA
voltage-gated calcium channel activity
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IBA
mechanosensitive ion channel activity
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IBA
cell component
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
stereocilium tip
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
integral component of membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
cellular component
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
ND
integral component of plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
biological process
ion transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
vestibular reflex
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDI7&geneProductId=UniProtKB:Q8TDI7
determination method
IEA
calcium ion transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
regulation of calcium ion transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
detection of mechanical stimulus involved in sensory perception of sound
determination method
IEA
IMP
2 references
retrieved
5 June 2018
stated in
Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDI7&geneProductId=UniProtKB:Q8TDI7
determination method
IMP
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDI7&geneProductId=UniProtKB:Q8TDI7
determination method
IEA
detection of mechanical stimulus involved in sensory perception of sound
determination method
IBA
IEA
IMP
3 references
retrieved
8 April 2019
stated in
Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function
GOA
curator
UniProt
UniProt protein ID
Q8TDI7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IBA
vestibular reflex
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDI7
determination method
IBA
has part(s)
TMC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8TDI7
Identifiers
RefSeq protein ID
NP_542789
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
117532
XP_005260717
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
117532
UniProt protein ID
Q8TDI7
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDI7
Ensembl protein ID
ENSP00000351732
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000351732
ENSP00000495303
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495303
Transporter Classification Database ID
1.A.17.4.1
1 reference
based on heuristic
TCDB BLAST
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