Wikidata

(Q21130015)

English

Ubiquitin conjugating enzyme E2 L3

mammalian protein found in Homo sapiens

  • ubiquitin-conjugating enzyme E2 L3
  • ubiquitin-conjugating enzyme E2-F1
  • ubiquitin conjugating enzyme E2L 3
  • ubiquitin-conjugating enzyme UBCH7
  • ubiquitin-protein ligase L3
  • UBE2L3
  • ubiquitin carrier protein L3
  • UbcH7
  • E2 ubiquitin-conjugating enzyme L3
  • L-UBC
In more languages

Statements

molecular function
ubiquitin-protein transferase activity
determination method
IDA
TAS
IMP
6 references
retrieved
17 October 2017
stated in
Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
TAS
retrieved
17 October 2017
stated in
A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
TAS
retrieved
17 October 2017
stated in
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IMP
retrieved
17 October 2017
stated in
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IDA
retrieved
17 October 2017
stated in
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IDA
retrieved
17 October 2017
stated in
Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IDA
protein binding
determination method
IPI
18 references
retrieved
17 October 2017
stated in
UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors
GOA
curator
UniProt
UniProt protein ID
P68036
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Structural basis for the inhibition of host protein ubiquitination by Shigella effector kinase OspG
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
retrieved
17 October 2017
stated in
Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P68036&geneProductId=UniProtKB:P68036
determination method
IPI
cell component
biological process

Identifiers

 
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