Wikidata

(Q21130029)

English

Host cell factor C1

mammalian protein found in Homo sapiens

  • HCFC1
  • VP16-accessory protein
  • VCAF
  • protein phosphatase 1, regulatory subunit 89
  • VP16 accessory protein
  • CFF
  • C1 factor
  • host cell factor 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
30 references
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
HCF-1 functions as a coactivator for the zinc finger protein Krox20
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Defining the human deubiquitinating enzyme interaction landscape
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
retrieved
8 April 2019
stated in
BAP1 is phosphorylated at serine 592 in S-phase following DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IEA
retrieved
8 April 2019
stated in
Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latency
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
retrieved
8 April 2019
stated in
The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
retrieved
8 April 2019
stated in
Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1)
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
retrieved
8 April 2019
stated in
Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
retrieved
8 April 2019
stated in
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
retrieved
8 April 2019
stated in
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1
GOA
curator
UniProt
UniProt protein ID
P51610
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51610
determination method
IDA
biological process

Identifiers

 
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