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Cytokine receptor like factor 1
mammalian protein found in Homo sapiens
cytokine-like factor 1
cytokine type 1 receptor CRLP-1
CLF-1
ZcytoR5
class I cytokine receptor
cytokine receptor-like factor 1
CRLF1
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O75462
part of
Fibronectin type III superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O75462
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O75462
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O75462
Fibronectin type III, protein family
1 reference
based on heuristic
inferred from protein domain or family
Growth hormone/erythropoietin receptor, ligand binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O75462
encoded by
CRLF1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O75462
molecular function
protein heterodimerization activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
ciliary neurotrophic factor receptor binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
cytokine activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IPI
cytokine binding
determination method
IPI
1 reference
retrieved
31 January 2018
stated in
Characterizing the new transcription regulator protein p60TRP
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O75462&geneProductId=UniProtKB:O75462
determination method
IPI
cytokine receptor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
cytokine binding
determination method
IBA
IPI
2 references
retrieved
8 April 2019
stated in
Characterizing the new transcription regulator protein p60TRP
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
cell component
extracellular region
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O75462
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IEA
CRLF-CLCF1 complex
determination method
IDA
1 reference
retrieved
31 January 2018
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O75462&geneProductId=UniProtKB:O75462
determination method
IDA
extracellular space
determination method
IEA
TAS
2 references
retrieved
31 January 2018
stated in
Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O75462&geneProductId=UniProtKB:O75462
determination method
TAS
retrieved
31 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O75462&geneProductId=UniProtKB:O75462
determination method
IEA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
TAS
extracellular space
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
TAS
external side of plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
receptor complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
CRLF-CLCF1 complex
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
biological process
negative regulation of neuron apoptotic process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
ureteric bud development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IEA
positive regulation of cell population proliferation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
negative regulation of motor neuron apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IEA
positive regulation of tyrosine phosphorylation of STAT protein
determination method
IDA
1 reference
retrieved
31 January 2018
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O75462&geneProductId=UniProtKB:O75462
determination method
IDA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IEA
cytokine-mediated signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
TAS
interleukin-27-mediated signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
TAS
positive regulation of tyrosine phosphorylation of STAT protein
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75462
determination method
IBA
has part(s)
Growth hormone/erythropoietin receptor, ligand binding
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O75462
fibronectin type III
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O75462
Identifiers
RefSeq protein ID
NP_004741
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9244
UniProt protein ID
O75462
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O75462
Ensembl protein ID
ENSP00000376188
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000376188
ENSP00000470625
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000470625
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