Wikidata

(Q21130805)

English

SHANK associated RH domain interactor

mammalian protein found in Homo sapiens

  • shank-associated RH domain-interacting protein
  • hSIPL1
  • sharpin
  • shank-interacting protein-like 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
Linear ubiquitination prevents inflammation and regulates immune signalling
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN is an endogenous inhibitor of β1-integrin activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
retrieved
8 April 2019
stated in
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IPI
cell component
LUBAC complex
determination method
IBA
IDA
6 references
retrieved
8 April 2019
stated in
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IDA
retrieved
8 April 2019
stated in
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IDA
retrieved
8 April 2019
stated in
Molecular Basis and Regulation of OTULIN-LUBAC Interaction
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IDA
retrieved
8 April 2019
stated in
Linear ubiquitination prevents inflammation and regulates immune signalling
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IDA
retrieved
8 April 2019
stated in
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
GOA
curator
UniProt
UniProt protein ID
Q9H0F6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H0F6
determination method
IBA
biological process

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21130805&oldid=2023013821"