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Nanos C2HC-type zinc finger 1
mammalian protein found in Homo sapiens
EC_Rep1a
nanos homolog 1
NANOS1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WY41
part of
Nanos/Xcat2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WY41
Nanos domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WY41
Zinc finger, nanos-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WY41
encoded by
NANOS1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WY41
molecular function
zinc ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
translation repressor activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
ISS
RNA binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IPI
retrieved
8 April 2019
stated in
NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IPI
retrieved
8 April 2019
stated in
The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IPI
retrieved
8 April 2019
stated in
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IPI
cell component
cytoplasm
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
retrieved
8 April 2019
stated in
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
retrieved
8 April 2019
stated in
Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
perinuclear region of cytoplasm
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
retrieved
8 April 2019
stated in
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
retrieved
8 April 2019
stated in
The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
biological process
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
regulation of translation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
cell migration
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
epithelial cell migration
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
GOA
curator
UniProt
UniProt protein ID
Q8WY41
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
negative regulation of translation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
posttranscriptional regulation of gene expression
determination method
IEA
IDA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
retrieved
8 April 2019
stated in
Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IDA
cerebellar neuron development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
tissue homeostasis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
regulation of cell growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WY41
determination method
IEA
has part(s)
Zinc finger, nanos-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WY41
Identifiers
RefSeq protein ID
NP_955631
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
340719
UniProt protein ID
Q8WY41
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WY41
Ensembl protein ID
ENSP00000393275
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000393275
ENSP00000345924
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000345924
PDB structure ID
4CQO
1 reference
stated in
UniProt
UniProt protein ID
Q8WY41
retrieved
9 August 2016
language of work or name
English
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