Wikidata

(Q21131010)

English

Stratifin

mammalian protein found in Homo sapiens

  • 14-3-3 protein sigma
  • epithelial cell marker protein 1
  • 14-3-3 sigma
  • SFN
In more languages

Statements

molecular function
protein binding
determination method
IPI
31 references
retrieved
8 April 2019
stated in
SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner
GOA
curator
UniProt
UniProt protein ID
P31947
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding
GOA
curator
UniProt
UniProt protein ID
P31947
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein
GOA
curator
UniProt
UniProt protein ID
P31947
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax
GOA
curator
UniProt
UniProt protein ID
P31947
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Bacterial co-expression of human Tau protein with protein kinase A and 14-3-3 for studies of 14-3-3/phospho-Tau interaction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
PTH inactivates the AKT survival pathway in the colonic cell line Caco-2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the p53 C-terminus bound to 14-3-3: implications for stabilization of the p53 tetramer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
The functional interactome landscape of the human histone deacetylase family
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
An expression screen reveals modulators of class II histone deacetylase phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
retrieved
8 April 2019
stated in
The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31947
determination method
IPI
cell component
biological process

Identifiers

PDB structure ID
 
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