(Q21131022)

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Kank N-terminal motif, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

6 references

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of neuron projection development

IBA

biological process

1 reference

8 April 2019

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

regulation of transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14678&geneProductId=UniProtKB:Q14678

negative regulation of actin filament polymerization

IEA

negative regulation of ruffle assembly

1 reference

8 April 2019

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of Rho protein signal transduction

1 reference

8 April 2019

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

positive regulation of wound healing

1 reference

8 April 2019

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14678&geneProductId=UniProtKB:Q14678

positive regulation of Wnt signaling pathway

IEA

1 reference

8 April 2019

Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of insulin receptor signaling pathway

1 reference

8 April 2019

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of cell migration

1 reference

8 April 2019

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of lamellipodium morphogenesis

1 reference

8 April 2019

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of substrate adhesion-dependent cell spreading

1 reference

8 April 2019

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

regulation of establishment of cell polarity

1 reference

8 April 2019

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

negative regulation of actin filament polymerization

3 references

8 April 2019

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Kank proteins: a new family of ankyrin-repeat domain-containing proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

regulation of Rho protein signal transduction

IBA

1 reference

8 April 2019

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

glomerular visceral epithelial cell migration

1 reference

8 April 2019

KANK deficiency leads to podocyte dysfunction and nephrotic syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

cell population proliferation

1 reference

8 April 2019

A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

actin cytoskeleton organization

1 reference

8 April 2019

A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14678

ankyrin repeat-containing domain

has part(s)

1 reference

ankyrin repeat

1 reference

Kank N-terminal motif

1 reference