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(Q21131540)
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Pyrin and HIN domain family member 1
mammalian protein found in Homo sapiens
pyrin and HIN domain-containing protein 1
PYHIN1
interferon-inducible protein X
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6K0P9
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6K0P9
encoded by
PYHIN1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6K0P9
molecular function
ubiquitin protein ligase binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IPI
double-stranded DNA binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IBA
cell component
nucleoplasm
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
nuclear speck
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
protein-containing complex
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
nucleolus
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IBA
biological process
cell cycle
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
protein destabilization
determination method
IMP
2 references
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
cellular response to interferon-alpha
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
positive regulation of DNA binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
positive regulation of transcription, DNA-templated
determination method
IDA
2 references
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
protein stabilization
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
positive regulation of protein localization to nucleus
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
positive regulation of ubiquitin-dependent protein catabolic process
determination method
IDA
IMP
2 references
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha1 functions as a negative regulator of HDM2.
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IMP
retrieved
9 May 2019
stated in
Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin
GOA
curator
UniProt
UniProt protein ID
Q6K0P9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IDA
activation of innate immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
cellular response to interferon-beta
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
activation of innate immune response
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IBA
positive regulation of interleukin-1 beta production
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IBA
cellular response to interferon-beta
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6K0P9
determination method
IBA
Identifiers
RefSeq protein ID
NP_689714
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
NP_945146
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
NP_945147
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
NP_945148
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
XP_005244987
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
XP_011507544
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
XP_011507545
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
XP_016855952
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
149628
UniProt protein ID
Q6K0P9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6K0P9
Ensembl protein ID
ENSP00000357117
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357117
ENSP00000357120
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357120
ENSP00000357122
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357122
ENSP00000376082
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000376082
ENSP00000376083
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000376083
ENSP00000407616
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000407616
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