(Q21132781)

English

Corneodesmosin

mammalian protein found in Homo sapiens

S protein
CDSN
corneodesmosin
differentiated keratinocyte S protein

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No description defined

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Statements

1 reference

13 November 2019

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15517

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Homo-oligomerization of human corneodesmosin is mediated by its N-terminal glycine loop domain

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15517&geneProductId=UniProtKB:Q15517

determination method or standard

IDA

cell component

extracellular region

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IEA

desmosome

determination method or standard

3 references

8 April 2019

Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

NAS

retrieved

8 April 2019

stated in

Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IDA

retrieved

8 April 2019

stated in

Increased expression of caspase-1 and interleukin-18 in peeling skin disease, and a novel mutation of corneodesmosin

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IDA

cell-cell junction

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

TAS

plasma membrane

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

TAS

biological process

cell adhesion

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

TAS

skin morphogenesis

determination method or standard

3 references

8 April 2019

Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IMP

retrieved

8 April 2019

stated in

Increased expression of caspase-1 and interleukin-18 in peeling skin disease, and a novel mutation of corneodesmosin

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IEA

keratinocyte differentiation

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

NAS

epidermis development

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

TAS

cornification

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

TAS

corneocyte desquamation

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Increased expression of caspase-1 and interleukin-18 in peeling skin disease, and a novel mutation of corneodesmosin

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IMP

negative regulation of cornification

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Increased expression of caspase-1 and interleukin-18 in peeling skin disease, and a novel mutation of corneodesmosin

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15517

determination method or standard

IMP

cell-cell adhesion

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15517&geneProductId=UniProtKB:Q15517

determination method or standard

IDA

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21132781)

Corneodesmosin

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