(Q21132803)

Translation initiation factor 2, alpha subunit, middle domain superfamily

1 reference

Translation initiation factor 2, alpha subunit, C-terminal

1 reference

Nucleic acid-binding, OB-fold

1 reference

RNA-binding domain, S1, protein family

1 reference

based on heuristic

inferred from protein domain or family

S1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

translation initiation factor activity

4 references

17 October 2017

Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

An efficient mammalian cell-free translation system supplemented with translation factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

1 reference

17 October 2017

The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

9 references

8 April 2019

The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon-subunit and their functions in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Interaction of recombinant human eIF2 subunits with eIF2B and eIF2alpha kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

translation initiation factor activity

HDA

5 references

8 April 2019

Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

An efficient mammalian cell-free translation system supplemented with translation factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

eukaryotic 48S preinitiation complex

IBA

cell component

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

8 April 2019

Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

1 reference

17 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

eukaryotic translation initiation factor 2B complex

IBA

1 reference

17 October 2017

Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05198&geneProductId=UniProtKB:P05198

IDA

glial limiting end-foot

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

translation initiation ternary complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

cytoplasmic stress granule

ISS

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

eukaryotic translation initiation factor 2 complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

eukaryotic translation initiation factor 2B complex

IBA

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

cellular response to heat

HDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

positive regulation of type B pancreatic cell apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

response to endoplasmic reticulum stress

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

GSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cells

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

response to manganese-induced endoplasmic reticulum stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

transmembrane transport

1 reference

8 April 2019

protein autophosphorylation

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

regulation of translation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

regulation of translational initiation in response to stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

negative regulation of guanyl-nucleotide exchange factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

PERK-mediated unfolded protein response

1 reference

8 April 2019

The endoplasmic reticulum stress response in aging and age-related diseases

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05198

NAS

has part(s)

RNA-binding domain, S1

1 reference

S1 domain

1 reference