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Calpastatin
mammalian protein found in Homo sapiens
calpain inhibitor
CAST
calpastatin
sperm BS-17 component
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P20810
part of
Calpastatin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20810
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Proteinase inhibitor I27, calpastatin, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P20810
encoded by
CAST
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P20810
molecular function
peptidase inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P20810
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IEA
cysteine-type endopeptidase inhibitor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P20810
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
The Ca(2+)-dependent interaction of calpastatin domain L with the C-terminal tail of the Cav1.2 channel
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IPI
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IPI
endopeptidase inhibitor activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Autoantibodies to calpastatin (an endogenous inhibitor for calcium-dependent neutral protease, calpain) in systemic rheumatic diseases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
TAS
RNA binding
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
P20810
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IDA
cadherin binding
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IDA
calcium-dependent cysteine-type endopeptidase inhibitor activity
determination method
IMP
1 reference
retrieved
26 September 2017
stated in
Characterization of a functional domain of human calpastatin
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IMP
protease binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IBA
RNA binding
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
P20810
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
HDA
calcium-dependent cysteine-type endopeptidase inhibitor activity
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Characterization of a functional domain of human calpastatin
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IBA
cadherin binding
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
HDA
cell component
endoplasmic reticulum
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IDA
membrane
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
Association of the calpain/calpastatin network with subcellular organelles
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IDA
cytosol
determination method
IDA
TAS
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IDA
retrieved
8 April 2019
stated in
Association of the calpain/calpastatin network with subcellular organelles
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IDA
endoplasmic reticulum
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IBA
membrane
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Association of the calpain/calpastatin network with subcellular organelles
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IBA
biological process
negative regulation of peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P20810
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IEA
negative regulation of type B pancreatic cell apoptotic process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IDA
inhibition of cysteine-type endopeptidase activity
determination method
IMP
1 reference
retrieved
26 September 2017
stated in
Characterization of a functional domain of human calpastatin
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P20810&geneProductId=UniProtKB:P20810
determination method
IMP
inhibition of cysteine-type endopeptidase activity
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Characterization of a functional domain of human calpastatin
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
IBA
presynaptic active zone organization
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20810
determination method
TAS
has part(s)
Proteinase inhibitor I27, calpastatin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P20810
Identifiers
RefSeq protein ID
NP_001035905
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035906
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035907
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035908
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035909
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035910
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001035911
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001177371
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001271141
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001271142
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317555
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317556
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317557
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317558
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317559
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317560
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317561
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317562
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001317563
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001741
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_775083
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
NP_001362246
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
831
UniProt protein ID
P20810
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P20810
Ensembl protein ID
ENSP00000312523
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000312523
ENSP00000339914
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000339914
ENSP00000343421
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000343421
ENSP00000379157
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000379157
ENSP00000379158
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000379158
ENSP00000422176
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422176
ENSP00000425721
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000425721
ENSP00000320319
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000320319
ENSP00000396558
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000396558
ENSP00000412374
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412374
ENSP00000421130
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421130
ENSP00000421230
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421230
ENSP00000422325
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422325
ENSP00000422466
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422466
ENSP00000422612
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422612
ENSP00000422677
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422677
ENSP00000422807
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422807
ENSP00000422831
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422831
ENSP00000422929
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422929
ENSP00000422951
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422951
ENSP00000422957
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422957
ENSP00000423638
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000423638
ENSP00000423846
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000423846
ENSP00000424160
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424160
ENSP00000425670
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000425670
ENSP00000425787
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000425787
ENSP00000426422
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426422
ENSP00000426946
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426946
ENSP00000427092
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000427092
ENSP00000427195
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000427195
ENSP00000432878
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000432878
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Wikinews
(0 entries)
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
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Multilingual sites
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