(Q21134067)

English

NADH:ubiquinone oxidoreductase subunit B3

mammalian protein found in Homo sapiens

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
NADH-ubiquinone oxidoreductase B12 subunit
complex I-B12
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFB3
CI-B12

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Statements

1 reference

13 November 2019

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43676

1 reference

13 November 2019

1 reference

13 November 2019

NADH dehydrogenase (ubiquinone) activity

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

IEA

mitochondrial respiratory chain complex I

4 references

27 March 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43676&geneProductId=UniProtKB:O43676

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43676&geneProductId=UniProtKB:O43676

27 March 2018

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43676&geneProductId=UniProtKB:O43676

27 March 2018

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43676&geneProductId=UniProtKB:O43676

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

IEA

mitochondrial respiratory chain complex I

5 references

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

IBA

biological process

electron transport chain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

IEA

mitochondrial electron transport, NADH to ubiquinone

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

NAS

mitochondrial respiratory chain complex I assembly

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43676

determination method

IBA

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1703

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

(Q21134067)

NADH:ubiquinone oxidoreductase subunit B3

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