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Serine incorporator 5
mammalian protein found in Homo sapiens
Axotomy-induced glycoprotein 3
serine incorporator 5
AIGP-3
SERINC5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VE9
part of
Serine incorporator 5
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86VE9
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VE9
encoded by
SERINC5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VE9
molecular function
L-serine transmembrane transporter activity
determination method
IBA
1 reference
retrieved
31 October 2017
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86VE9&geneProductId=UniProtKB:Q86VE9
determination method
IBA
L-serine transmembrane transporter activity
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86VE9&geneProductId=UniProtKB:Q86VE9
determination method
TAS
cell component
extracellular exosome
determination method
IDA
1 reference
retrieved
31 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86VE9&geneProductId=UniProtKB:Q86VE9
determination method
IDA
Golgi apparatus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
myelin sheath
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
perinuclear region of cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
plasma membrane
determination method
IDA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
retrieved
8 April 2019
stated in
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
retrieved
8 April 2019
stated in
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
extracellular exosome
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
HDA
biological process
phospholipid biosynthetic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
innate immune response
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
retrieved
8 April 2019
stated in
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
retrieved
8 April 2019
stated in
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
L-serine transport
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86VE9&geneProductId=UniProtKB:Q86VE9
determination method
IEA
positive regulation of serine C-palmitoyltransferase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
ISS
phosphatidylserine metabolic process
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
detection of virus
determination method
IDA
2 references
retrieved
8 April 2019
stated in
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
retrieved
8 April 2019
stated in
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
myelination
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
viral process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
lipid metabolism
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
ISS
defense response to virus
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
retrieved
8 April 2019
stated in
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
retrieved
8 April 2019
stated in
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
GOA
curator
UniProt
UniProt protein ID
Q86VE9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IDA
sphingolipid metabolic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
IEA
L-serine biosynthetic process
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VE9
determination method
TAS
Identifiers
RefSeq protein ID
NP_001167542
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
NP_001167543
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
NP_840060
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
XP_011541606
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
XP_016864812
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
XP_016864813
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
XP_016864815
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
XP_024301781
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
256987
UniProt protein ID
Q86VE9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VE9
Ensembl protein ID
ENSP00000421665
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421665
ENSP00000426134
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426134
ENSP00000426237
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426237
ENSP00000488864
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000488864
Transporter Classification Database ID
9.A.29.3.5
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
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