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Zinc finger protein 451
mammalian protein found in Homo sapiens
E3 SUMO-protein ligase ZNF451
ZNF451
E3 SUMO-protein transferase ZNF451
coactivator for steroid receptors
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y4E5
part of
Zinc finger C2H2-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y4E5
encoded by
ZNF451
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y4E5
molecular function
SUMO ligase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IDA
transcription corepressor activity
determination method
IMP
2 references
retrieved
27 March 2018
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4E5&geneProductId=UniProtKB:Q9Y4E5
determination method
IMP
retrieved
8 April 2019
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IMP
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
A human MAP kinase interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IPI
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
nucleic acid binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
ISA
NAS
2 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
ISA
RNA polymerase II core promoter sequence-specific DNA binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IBA
cell component
PML body
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
nucleus
determination method
IDA
IEA
2 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4E5&geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
retrieved
5 June 2018
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4E5&geneProductId=UniProtKB:Q9Y4E5
determination method
IDA
nucleoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
nucleus
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
retrieved
8 April 2019
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IBA
histone methyltransferase complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IBA
biological process
negative regulation of transcription initiation from RNA polymerase II promoter
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IMP
negative regulation of histone H3-K9 acetylation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4E5&geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
negative regulation of transforming growth factor beta receptor signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IMP
protein sumoylation
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
retrieved
8 April 2019
stated in
Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IDA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y4E5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4E5&geneProductId=UniProtKB:Q9Y4E5
determination method
IEA
regulation of gene expression
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4E5
determination method
IBA
has part(s)
Zinc finger C2H2-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y4E5
Identifiers
RefSeq protein ID
NP_001026794
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
NP_001244202
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
NP_056370
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
XP_005249051
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
XP_011512762
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
XP_011512763
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
XP_011512764
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
XP_011512765
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26036
UniProt protein ID
Q9Y4E5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y4E5
Ensembl protein ID
ENSP00000350083
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000350083
ENSP00000359740
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359740
ENSP00000359742
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359742
ENSP00000359736
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359736
ENSP00000359744
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359744
ENSP00000421645
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421645
ENSP00000421786
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421786
ENSP00000424329
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424329
ENSP00000424723
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424723
ENSP00000425047
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000425047
ENSP00000427558
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000427558
ENSP00000476915
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000476915
PDB structure ID
5D2M
1 reference
stated in
UniProt
UniProt protein ID
Q9Y4E5
retrieved
21 March 2016
language of work or name
English
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