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Rho GTPase activating protein 12
mammalian protein found in Homo sapiens
rho-type GTPase-activating protein 12
rho GTPase-activating protein 12
ARHGAP12
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IWW6
part of
SH3-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
Rho GTPase activation protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
WW domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
ARHGAP12, SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Rho GTPase-activating protein domain family
1 reference
based on heuristic
inferred from protein domain or family
WW domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IWW6
encoded by
ARHGAP12
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IWW6
molecular function
GTPase activator activity
determination method
IEA
TAS
2 references
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWW6&geneProductId=UniProtKB:Q8IWW6
determination method
TAS
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IWW6&geneProductId=UniProtKB:Q8IWW6
determination method
IEA
GTPase activator activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IEA
cell component
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
TAS
phagocytic cup
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IDA
cytoplasm
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IBA
biological process
positive regulation of GTPase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IEA
regulation of small GTPase mediated signal transduction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
TAS
morphogenesis of an epithelial sheet
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
miR-199a-5p regulates urothelial permeability and may play a role in bladder pain syndrome
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IMP
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IEA
phagocytosis, engulfment
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IMP
actin filament organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IMP
negative regulation of small GTPase mediated signal transduction
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins
GOA
curator
UniProt
UniProt protein ID
Q8IWW6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IMP
regulation of GTPase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IWW6
determination method
IBA
has part(s)
WW domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
Rho GTPase-activating protein domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
ARHGAP12, SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IWW6
Identifiers
RefSeq protein ID
NP_001257624
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
NP_001257625
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
NP_001257626
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
NP_001257627
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
NP_001257628
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
NP_060757
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
XP_005252701
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
XP_011518063
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
XP_016872443
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
94134
UniProt protein ID
Q8IWW6
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IWW6
Ensembl protein ID
ENSP00000310984
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000310984
ENSP00000345808
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000345808
ENSP00000364399
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000364399
ENSP00000379448
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000379448
ENSP00000364394
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000364394
ENSP00000398050
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000398050
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