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Rhotekin 2
mammalian protein found in Homo sapiens
pleckstrin homology domain-containing family K member 1
rhotekin-2
RTKN2
PH domain-containing family K member 1
In more languages
default for all languages
No label defined
No description defined
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IZC4
part of
Rhotekin-2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IZC4
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IZC4
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
HR1 rho-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Anillin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IZC4
encoded by
RTKN2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IZC4
cell component
nucleus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2.
GOA
curator
UniProt
UniProt protein ID
Q8IZC4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IDA
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2.
GOA
curator
UniProt
UniProt protein ID
Q8IZC4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IDA
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IEA
biological process
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IEA
hemopoiesis
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZC4&geneProductId=UniProtKB:Q8IZC4
determination method
IEA
positive regulation of cell population proliferation
determination method
IBA
1 reference
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZC4&geneProductId=UniProtKB:Q8IZC4
determination method
IBA
hemopoiesis
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IBA
positive regulation of NF-kappaB transcription factor activity
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes.
GOA
curator
UniProt
UniProt protein ID
Q8IZC4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IMP
positive regulation of NIK/NF-kappaB signaling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes.
GOA
curator
UniProt
UniProt protein ID
Q8IZC4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IMP
negative regulation of intrinsic apoptotic signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes.
GOA
curator
UniProt
UniProt protein ID
Q8IZC4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IMP
positive regulation of cell population proliferation
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZC4
determination method
IBA
has part(s)
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IZC4
Anillin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IZC4
HR1 rho-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8IZC4
Identifiers
RefSeq protein ID
NP_001269870
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
NP_660350
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
XP_011537758
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
XP_011537759
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
XP_011537762
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
XP_016871332
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
XP_016871333
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
219790
UniProt protein ID
Q8IZC4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8IZC4
Ensembl protein ID
ENSP00000362894
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000362894
ENSP00000378678
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000378678
ENSP00000325379
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000325379
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