(Q21135479)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UQD0

Voltage-dependent channel domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UQD0

Voltage gated sodium channel

1 reference

Transporter Classification Database ID

1.A.1.10.8

2 October 2019

hierarchical database ID heuristic

Sodium ion transport-associated domain, protein family

1 reference

Ion transport domain, protein family

1 reference

Voltage-gated Na+ ion channel, cytoplasmic domain, protein family

1 reference

IQ motif, EF-hand binding site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

sodium channel activity

1 reference

8 April 2019

voltage-gated ion channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

3 references

8 April 2019

Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

voltage-gated sodium channel activity

IPI

5 references

27 February 2018

Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

27 February 2018

De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

27 February 2018

Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

27 February 2018

Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

voltage-gated sodium channel activity

IDA

6 references

8 April 2019

Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

voltage-gated sodium channel complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

membrane depolarization during action potential

biological process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

peripheral nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

3 references

8 April 2019

Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

regulation of ion transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

nervous system development

1 reference

8 April 2019

Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

ion transmembrane transport

TAS

1 reference

27 February 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

transmembrane transport

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

neuronal action potential

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

sodium ion transmembrane transport

1 reference

27 February 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQD0&geneProductId=UniProtKB:Q9UQD0

sodium ion transmembrane transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQD0

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2625

language of work or name

English

http://purl.uniprot.org/uniprot/Q9UQD0

17 August 2016

exact match

1 reference

http://www.uniprot.org/uniprot/Q9WTU3.txt?version=127

Identifiers.org

Identifiers

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 November 2015

Transporter Classification Database ID

1.A.1.10.8

2 references

Transporter Classification database

13 March 2020

Transporter Classification database