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(Q21136814)
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English
Zinc and ring finger 2
mammalian protein found in Homo sapiens
zinc and ring finger 2, E3 ubiquitin protein ligase
RING finger protein 202
E3 ubiquitin-protein ligase ZNRF2
zinc finger/RING finger 2
protein Ells2
zinc/RING finger protein 2
RING-type E3 ubiquitin transferase ZNRF2
ZNRF2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NHG8
part of
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NHG8
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NHG8
encoded by
ZNRF2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NHG8
molecular function
ubiquitin protein ligase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IDA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
ubiquitin-protein transferase activity
determination method
EXP
TAS
2 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NHG8&geneProductId=UniProtKB:Q8NHG8
determination method
TAS
retrieved
1 January 2018
stated in
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NHG8&geneProductId=UniProtKB:Q8NHG8
determination method
EXP
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
cell component
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IDA
lysosomal membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
endosome membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
cytoplasmic vesicle membrane
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IDA
presynaptic membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
synapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
lysosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
endosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
plasma membrane
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
retrieved
8 April 2019
stated in
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IDA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
TAS
protein-containing complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IDA
biological process
protein ubiquitination
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8NHG8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
IEA
protein polyubiquitination
determination method
IBA
TAS
2 references
retrieved
27 March 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NHG8&geneProductId=UniProtKB:Q8NHG8
determination method
TAS
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NHG8&geneProductId=UniProtKB:Q8NHG8
determination method
IBA
proteasome-mediated ubiquitin-dependent protein catabolic process
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NHG8&geneProductId=UniProtKB:Q8NHG8
determination method
IBA
protein polyubiquitination
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NHG8
determination method
TAS
has part(s)
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8NHG8
Identifiers
RefSeq protein ID
NP_667339
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
223082
UniProt protein ID
Q8NHG8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8NHG8
Ensembl protein ID
ENSP00000323879
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000323879
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