(Q21147970)

English

Glutamate decarboxylase 2

mammalian protein found in Homo sapiens

glutamate decarboxylase 65 kDa isoform
GAD-65
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
glutamate decarboxylase 2
65 kDa glutamic acid decarboxylase
GAD2
Glutamate decarboxylase-2 (pancreas)

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Pyridoxal phosphate-dependent transferase, major domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05329

Pyridoxal phosphate-dependent decarboxylase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05329

Pyridoxal phosphate-dependent transferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05329

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Pyridoxal-phosphate binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

catalytic activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

protein heterodimerization activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

glutamate binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

glutamate decarboxylase activity

determination method

Golgi apparatus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

plasma membrane

determination method

2 references

clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

inhibitory synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

synaptic vesicle membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

anchored component of membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

presynaptic membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

biological process

carboxylic acid metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

neurotransmitter biosynthetic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

chemical synaptic transmission

determination method

1 reference

8 April 2019

Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

neurotransmitter secretion

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05329

determination method

Pyridoxal-phosphate binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05329

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000259271

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000259271

ENSP00000365437

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365437

ENSP00000390434

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000390434

ENSP00000498009

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498009

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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