(Q21154955)

Protein kinase-like domain superfamily

1 reference

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

1 December 2016

1 reference

17 December 2016

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

IEA

protein kinase activity

1 reference

1 January 2018

13 references

1 January 2018

Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

MAP kinase kinase kinase activity

IPI

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

2 references

2 references

protein serine/threonine kinase activity

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

intracellular membrane-bounded organelle

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

tumor necrosis factor-mediated signaling pathway

IEA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

cellular response to mechanical stimulus

IEA

1 reference

1 January 2018

Expression of the Bcl-2 protein BAD promotes prostate cancer growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

positive regulation of I-kappaB kinase/NF-kappaB signaling

IEP

1 reference

16 July 2018

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99558&geneProductId=UniProtKB:Q99558

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

IMP

NIK/NF-kappaB signaling

1 reference

1 January 2018

regulation of mitotic cell cycle

TAS

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99558&geneProductId=UniProtKB:Q99558

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

stress-activated protein kinase signaling cascade

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

activation of protein kinase activity

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99558

regulation of apoptotic process

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99558&geneProductId=UniProtKB:Q99558

positive regulation of I-kappaB kinase/NF-kappaB signaling

serine/threonine-protein kinase, active site

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

Identifiers

1 reference

17 December 2016

1 reference

17 December 2016

1 reference

1 December 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016