(Q21172630)

http://www.ebi.ac.uk/interpro/protein/Q8TDN7

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

13 November 2019

1 reference

13 November 2019

dihydroceramidase activity

1 reference

7 November 2018

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

N-acylsphingosine amidohydrolase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

dihydroceramidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

endoplasmic reticulum

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

cellular response to calcium ion

biological process

1 reference

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

regulation of lipid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

1 reference

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

sphingosine biosynthetic process

IMP

2 references

7 November 2018

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

7 November 2018

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

response to alkaline pH

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

keratinocyte differentiation

1 reference

8 April 2019

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

ceramide metabolic process

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

epidermis development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

sphingolipid metabolic process

regulation of water loss via skin

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

sphingosine biosynthetic process

4 references

8 April 2019

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

ceramide catabolic process

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

sebaceous gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7