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(Q21172736)
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Connector enhancer of kinase suppressor of Ras 2
mammalian protein found in Homo sapiens
membrane-associated guanylate kinase-interacting protein
connector enhancer of KSR2
connector enhancer of kinase suppressor of ras 2
CNK homolog protein 2
CNKSR2
CNK2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXI2
part of
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
PDZ superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
Sterile alpha motif/pointed domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Connector enhancer of kinase suppressor of ras 2, protein family
1 reference
based on heuristic
inferred from protein domain or family
Sterile alpha motif domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
PDZ domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
CRIC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXI2
encoded by
CNKSR2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXI2
molecular function
identical protein binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IPI
cell component
cytoplasm
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
neuron projection
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
neuronal cell body
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
postsynaptic membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
extracellular exosome
determination method
IDA
1 reference
retrieved
17 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q8WXI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8WXI2&geneProductId=UniProtKB:Q8WXI2
determination method
IDA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8WXI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
postsynaptic density
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
extracellular exosome
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q8WXI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
HDA
glutamatergic synapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
extrinsic component of postsynaptic density membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
biological process
regulation of signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
postsynapse organization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WXI2
determination method
IEA
has part(s)
Connector enhancer of kinase suppressor of ras 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
CRIC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
sterile alpha motif domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
PDZ domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8WXI2
Identifiers
RefSeq protein ID
NP_001162118
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001162119
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001162120
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001317699
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001317700
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001317701
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_001317702
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
NP_055742
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
XP_011543773
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
XP_011543774
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
XP_016884847
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
22866
UniProt protein ID
Q8WXI2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8WXI2
Ensembl protein ID
ENSP00000279451
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000279451
ENSP00000368824
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000368824
ENSP00000397906
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000397906
ENSP00000444633
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000444633
ENSP00000495189
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495189
ENSP00000496186
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000496186
ENSP00000496573
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000496573
ENSP00000495954
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495954
ENSP00000496709
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000496709
ENSP00000495695
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495695
ENSP00000496088
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000496088
ENSP00000495325
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495325
ENSP00000495501
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495501
ENSP00000494416
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494416
ENSP00000494115
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494115
ENSP00000494962
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494962
ENSP00000494983
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494983
ENSP00000494906
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000494906
ENSP00000495012
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000495012
PDB structure ID
2EAN
1 reference
stated in
UniProt
UniProt protein ID
Q8WXI2
retrieved
9 August 2016
language of work or name
English
3BS5
1 reference
stated in
UniProt
UniProt protein ID
Q8WXI2
retrieved
9 August 2016
language of work or name
English
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