(Q21172941)

http://www.ebi.ac.uk/interpro/protein/P55008

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

EF-hand domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

24 April 2018

X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

actin filament binding

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

4 references

8 April 2019

X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

actin filament binding

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

10 September 2018

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

actin filament binding

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

perinuclear region of cytoplasm

1 reference

8 April 2019

IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

NFAT regulates the expression of AIF-1 and IRT-1: yin and yang splice variants of neointima formation and atherosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

10 September 2018

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

3 references

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

The allograft inflammatory factor-1 in Creutzfeldt-Jakob disease brains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to extracellular stimulus

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of smooth muscle cell chemotaxis

1 reference

8 April 2019

NFAT regulates the expression of AIF-1 and IRT-1: yin and yang splice variants of neointima formation and atherosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

negative regulation of smooth muscle cell proliferation

positive regulation of cell migration

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

positive regulation of muscle hyperplasia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of nitric oxide biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of monocyte chemotaxis

1 reference

8 April 2019

AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

negative regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

response to glucocorticoid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

response to electrical stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

negative regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to hydroperoxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

microglial cell activation

1 reference

8 April 2019

X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of G1/S transition of mitotic cell cycle

NAS

3 references

8 April 2019

Overexpression of allograft inflammatory factor-1 promotes proliferation of vascular smooth muscle cells by cell cycle deregulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Overexpression of allograft inflammatory factor-1 promotes the proliferation and migration of human endothelial cells (HUV-EC-C) probably by up-regulation of basic fibroblast growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

actin filament polymerization

1 reference

8 April 2019

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

negative regulation of smooth muscle cell chemotaxis

1 reference

8 April 2019

NFAT regulates the expression of AIF-1 and IRT-1: yin and yang splice variants of neointima formation and atherosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to hormone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

response to axon injury

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of T cell proliferation

1 reference

8 April 2019

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to interferon-gamma

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to morphine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection

inflammatory response

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

3 references

24 April 2018

X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55008&geneProductId=UniProtKB:P55008

positive regulation of T cell migration

1 reference

8 April 2019

Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of smooth muscle cell proliferation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

NFAT regulates the expression of AIF-1 and IRT-1: yin and yang splice variants of neointima formation and atherosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cerebellum development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

actin filament bundle assembly

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Structural and functional characterization of human Iba proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

4 references

8 April 2019

X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of cell population proliferation

1 reference

8 April 2019

Overexpression of allograft inflammatory factor-1 promotes the proliferation and migration of human endothelial cells (HUV-EC-C) probably by up-regulation of basic fibroblast growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

regulation of gene expression

1 reference

8 April 2019

Allograft inflammatory factor-1 stimulates chemokine production and induces chemotaxis in human peripheral blood mononuclear cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

cellular response to oxidative stress

HDA

1 reference

8 April 2019

The allograft inflammatory factor-1 in Creutzfeldt-Jakob disease brains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of chemotaxis

1 reference

8 April 2019

Allograft inflammatory factor-1 stimulates chemokine production and induces chemotaxis in human peripheral blood mononuclear cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of mononuclear cell migration

1 reference

8 April 2019

Allograft inflammatory factor-1 stimulates chemokine production and induces chemotaxis in human peripheral blood mononuclear cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

positive regulation of fibroblast growth factor production

1 reference

8 April 2019

Overexpression of allograft inflammatory factor-1 promotes the proliferation and migration of human endothelial cells (HUV-EC-C) probably by up-regulation of basic fibroblast growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55008

1 reference

Analyzing microglial phenotypes across neuropathologies: a practical guide

brain perivascular macrophage

1 reference

stated in

Analyzing microglial phenotypes across neuropathologies: a practical guide

has part(s)

EF-hand domain

1 reference

stated in

InterPro Release 71.0