(Q21173216)

KA1 domain/Ssp2, C-terminal

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Maternal embryonic leucine zipper kinase, catalytic domain, protein family

1 reference

Kinase associated domain 1 (KA1), protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

Substrate specificity and activity regulation of protein kinase MELK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

protein serine/threonine kinase activity

7 references

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

Substrate specificity and activity regulation of protein kinase MELK

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

24 October 2017

Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

4 references

8 April 2019

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

protein serine/threonine kinase activity

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

CDC25B phosphorylated by pEg3 localizes to the centrosome and the spindle poles at mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Substrate specificity and activity regulation of protein kinase MELK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

non-membrane spanning protein tyrosine kinase activity

IBA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Substrate specificity and activity regulation of protein kinase MELK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

24 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

Cell-cycle-dependent cortical localization of pEg3 protein kinase in Xenopus and human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

intrinsic apoptotic signaling pathway in response to oxidative stress

IBA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

intracellular signal transduction

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14680&geneProductId=UniProtKB:Q14680

protein phosphorylation

1 reference

24 October 2017

G2/M transition of mitotic cell cycle

1 reference

8 April 2019

Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

protein autophosphorylation

TAS

1 reference

8 April 2019

Substrate specificity and activity regulation of protein kinase MELK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

cell population proliferation

1 reference

8 April 2019

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

peptidyl-tyrosine phosphorylation

IDA

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14680

http://www.uniprot.org/uniprot/Q14680.txt?version=149

EC enzyme number

2.7.10.2

1 reference

14 November 2015

has part(s)

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

serine/threonine-protein kinase, active site

1 reference

Kinase associated domain 1 (KA1)

1 reference

Maternal embryonic leucine zipper kinase, catalytic domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016