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Eukaryotic translation initiation factor 4H
mammalian protein found in Homo sapiens
EIF4H
Williams-Beuren syndrome chromosomal region 1 protein
eukaryotic translation initiation factor 4H
Williams-Beuren syndrome chromosome region 1
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15056
part of
RNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15056
Nucleotide-binding alpha-beta plait domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15056
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
eIF4H, RNA recognition motif, protein family
1 reference
based on heuristic
inferred from protein domain or family
RNA recognition motif domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15056
encoded by
EIF4H
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15056
molecular function
translation factor activity, RNA binding
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IPI
nucleic acid binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
ribosomal small subunit binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
RNA strand-exchange activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
helicase activity
determination method
TAS
1 reference
retrieved
26 September 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
TAS
RNA strand annealing activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
RNA binding
determination method
IDA
IEA
TAS
4 references
retrieved
26 September 2017
stated in
Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
TAS
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
IEA
retrieved
26 September 2017
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
IDA
retrieved
26 September 2017
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
IDA
translation initiation factor activity
determination method
IBA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
cadherin binding
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
IDA
RNA binding
determination method
HDA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
retrieved
8 April 2019
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
HDA
retrieved
8 April 2019
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
HDA
cadherin binding
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
E-cadherin interactome complexity and robustness resolved by quantitative proteomics
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
HDA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
perinuclear region of cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
eukaryotic translation initiation factor 4F complex
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
membrane
determination method
IDA
1 reference
retrieved
26 September 2017
stated in
Defining the membrane proteome of NK cells
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15056&geneProductId=UniProtKB:Q15056
determination method
IDA
polysome
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
membrane
determination method
HDA
1 reference
retrieved
8 April 2019
stated in
Defining the membrane proteome of NK cells
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
HDA
biological process
translational initiation
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
viral process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
developmental growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
sexual reproduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
regulation of translational initiation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
TAS
protein biosynthesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q15056
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IEA
eukaryotic translation initiation factor 4F complex assembly
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
formation of translation preinitiation complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
cytoplasmic translation
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15056
determination method
IBA
physically interacts with
Viroporin 3a
determination method
Affinity Capture-MS
1 reference
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
has part(s)
RNA recognition motif domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15056
eIF4H, RNA recognition motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q15056
Identifiers
RefSeq protein ID
NP_071496
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7458
NP_114381
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7458
UniProt protein ID
Q15056
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q15056
Ensembl protein ID
ENSP00000265753
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000265753
ENSP00000265754
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000265754
PDB structure ID
2DNG
1 reference
stated in
Swiss-Prot
UniProt
retrieved
9 November 2015
reference URL
http://www.uniprot.org/uniprot/Q9WUK2.txt?version=128
Sitelinks
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