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(Q21173485)
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Hydroxycarboxylic acid receptor 2
mammalian protein found in Homo sapiens
G-protein coupled receptor HM74A
HCAR2
nicotinic acid receptor
niacin receptor 1
hydroxycarboxylic acid receptor 2
G-protein coupled receptor 109A
hydroxy-carboxylic acid receptor 2
G protein-coupled receptor HM74a
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDS4
part of
Hydroxycarboxylic acid receptor 2/3
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8TDS4
membrane proteins
1 reference
based on heuristic
inferred from GOA cell component → membrane
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDS4
encoded by
HCAR2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDS4
molecular function
nicotinic acid receptor activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
ISS
G protein-coupled receptor activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
signal transducer activity
determination method
IEA
1 reference
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDS4&geneProductId=UniProtKB:Q8TDS4
determination method
IEA
cell component
integral component of membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
cell junction
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IDA
plasma membrane
determination method
IDA
TAS
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
retrieved
8 April 2019
stated in
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
biological process
apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
negative regulation of lipid catabolic process
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
ISS
positive regulation of adiponectin secretion
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
ISS
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
positive regulation of neutrophil apoptotic process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IDA
neutrophil apoptotic process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IDA
G protein-coupled receptor signaling pathway
determination method
IEA
TAS
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8TDS4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDS4
determination method
IEA
physically interacts with
acifran
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
1595
language of work or name
English
retrieved
17 August 2016
acipimox
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
1596
language of work or name
English
retrieved
17 August 2016
(E)-cinnamic acid
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
3203
language of work or name
English
retrieved
17 August 2016
nicotinic acid
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
1588
language of work or name
English
retrieved
17 August 2016
(E)-p-coumaric acid
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5787
language of work or name
English
retrieved
17 August 2016
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8TDS4
Identifiers
RefSeq protein ID
NP_808219
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
338442
UniProt protein ID
Q8TDS4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q8TDS4
Ensembl protein ID
ENSP00000375066
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000375066
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