(Q21201272)

English

Apolipoprotein A-IV

human protein (annotated by UniProtKB/Swiss-Prot P06727)

Apolipoprotein A4

In more languages

Statements

0 references

Apolipoprotein A/E

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06727

1 reference

UniProt protein ID

17 September 2016

1 reference

UniProt protein ID

9 August 2016

language of work or name

molecular function

protein homodimerization activity

determination method

1 reference

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

phosphatidylcholine-sterol O-acyltransferase activator activity

determination method

1 reference

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

cholesterol transfer activity

determination method

1 reference

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

phosphatidylcholine binding

determination method

protein binding

determination method

1 reference

8 April 2019

Apolipoprotein A-IV reduces hepatic gluconeogenesis through nuclear receptor NR1D1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

cholesterol binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

antioxidant activity

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

copper ion binding

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

lipid transporter activity

determination method

1 reference

8 April 2019

The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

identical protein binding

determination method

1 reference

8 April 2019

The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

phospholipid binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

phosphatidylcholine binding

determination method

3 references

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

blood microparticle

determination method

1 reference

31 October 2017

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

endoplasmic reticulum lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

extracellular exosome

determination method

determination method

1 reference

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

extracellular space

determination method

3 references

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

extracellular matrix

determination method

1 reference

31 October 2017

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

extracellular region

determination method

5 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

The human plasma proteome: a nonredundant list developed by combination of four separate sources

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

31 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

extracellular region

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

extracellular space

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

high-density lipoprotein particle

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

collagen-containing extracellular matrix

determination method

1 reference

8 April 2019

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

extracellular exosome

determination method

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

blood microparticle

determination method

1 reference

8 April 2019

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

biological process

negative regulation of plasma lipoprotein oxidation

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

positive regulation of cholesterol esterification

determination method

1 reference

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

positive regulation of lipoprotein lipase activity

determination method

1 reference

31 October 2017

Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

removal of superoxide radicals

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

leukocyte cell-cell adhesion

determination method

1 reference

8 April 2019

Apolipoprotein A-IV inhibits experimental colitis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

phosphatidylcholine metabolic process

determination method

1 reference

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

lipid transport

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

hydrogen peroxide catabolic process

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

reverse cholesterol transport

determination method

1 reference

31 October 2017

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

phospholipid efflux

determination method

1 reference

31 October 2017

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

triglyceride homeostasis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

cholesterol biosynthetic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

high-density lipoprotein particle assembly

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

retinoid metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

high-density lipoprotein particle remodeling

determination method

1 reference

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

lipid homeostasis

determination method

1 reference

8 April 2019

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

cholesterol metabolic process

determination method

1 reference

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

positive regulation of triglyceride catabolic process

determination method

1 reference

31 October 2017

Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

response to stilbenoid

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

positive regulation of fatty acid biosynthetic process

determination method

1 reference

31 October 2017

Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

very-low-density lipoprotein particle remodeling

determination method

1 reference

31 October 2017

Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

regulation of cholesterol transport

determination method

1 reference

31 October 2017

Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

protein-lipid complex assembly

determination method

1 reference

8 April 2019

Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

response to lipid hydroperoxide

determination method

1 reference

8 April 2019

Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

neuron projection regeneration

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

cholesterol homeostasis

determination method

1 reference

31 October 2017

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

lipoprotein metabolic process

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06727&geneProductId=UniProtKB:P06727

determination method

lipid catabolic process

determination method

1 reference

8 April 2019

Plasma metabolism of apolipoprotein A-IV in humans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

triglyceride catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

regulation of cholesterol transport

determination method

cholesterol efflux

determination method

3 references

8 April 2019

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

positive regulation of lipid biosynthetic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06727

determination method

Identifiers

UniProt protein ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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