Wikidata

(Q21418771)

English

Histocompatibility 2, class II antigen A, beta 1

mammalian protein found in Mus musculus

  • MHC class II antigen A beta
  • H-2 class II histocompatibility antigen, A beta chain
  • response to metastatic cancers 1
  • histocompatibility 2, class II antigen A, beta 1
  • MHC class II H2-IA-beta-psi
  • major histocompatibility complex class II beta chain
  • H2-Ab1
In more languages

Statements

molecular function
cell component
MHC class II protein complex
determination method
IDA
IEA
10 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P14483
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IEA
retrieved
9 May 2019
stated in
Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Antigen presentation and T cell development in H2-M-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking the MHC class II-associated invariant chain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Altered antigen presentation in mice lacking H2-O
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
external side of plasma membrane
determination method
IDA
9 references
retrieved
9 May 2019
stated in
Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Antigen presentation and T cell development in H2-M-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking the MHC class II-associated invariant chain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Cell-mediated fas-based lysis of dendritic cells which are apparently resistant to anti-Fas antibody
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Accelerated antigen presentation and elicitation of humoral response in vivo by FcgammaRIIB- and FcgammaRI/III-mediated immune complex uptake
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Altered antigen presentation in mice lacking H2-O
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
biological process
antigen processing and presentation of exogenous peptide antigen via MHC class II
determination method
IDA
8 references
retrieved
9 May 2019
stated in
MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance?
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
The impact of H2-DM on humoral immune responses
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking the MHC class II-associated invariant chain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Altered antigen presentation in mice lacking H2-O
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
cellular response to interferon-gamma
determination method
IDA
5 references
retrieved
9 May 2019
stated in
IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
I-A beta gene expression regulation in macrophages derived from mice susceptible or resistant to infection with M. bovis BCG
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Differential regulation of B7 mRNA in enterocytes and lymphoid cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
Interferon-gamma activates multiple pathways to regulate the expression of the genes for major histocompatibility class II I-A beta, tumor necrosis factor and complement component C3 in mouse macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA
retrieved
9 May 2019
stated in
The expression of I-A correlates with the uptake of interferon-gamma by macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14483
determination method
IDA

Identifiers

 
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