(Q21494743)

Adaptor protein Cbl, N-terminal domain superfamily

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

protein kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

3 references

14 February 2019

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

identical protein binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

protein serine/threonine kinase activity

ISO

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

JUN kinase kinase kinase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

programmed cell death

1 reference

14 February 2019

protein homotrimerization

3 references

protein phosphorylation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

intracellular signal transduction

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9D2Y4&geneProductId=UniProtKB:Q9D2Y4

cell surface receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9D2Y4

protein phosphorylation

1 reference

14 February 2019

serine-threonine/tyrosine-protein kinase, catalytic domain

has part(s)

1 reference

protein kinase domain

1 reference