(Q21495004)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

IPI

hyaluronic acid binding

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

1 reference

14 February 2019

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

epidermal growth factor receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

phosphoprotein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

transmembrane signaling receptor activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

cytokine receptor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

hyaluronic acid binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

integral component of membrane

cell component

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

macrophage migration inhibitory factor receptor complex

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

Hyaluronan is a prerequisite for ductal branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Tetraspanin CD151 promotes cell migration by regulating integrin trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

external side of plasma membrane

29 references

14 February 2019

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Accessory protein-like is essential for IL-18-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CDK6 kinase activity is required for thymocyte development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

GATA-3 is required for early T lineage progenitor development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

How defects in central tolerance impinge on a deficiency in regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

GATA-3 regulates the development and function of invariant NKT cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

STAT5 is required for thymopoiesis in a development stage-specific manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD1 recognition by mouse NK1+ T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

apical plasma membrane

ISS

2 references

lamellipodium membrane

2 references

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Hyaluronan is a prerequisite for ductal branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

basolateral plasma membrane

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

macrophage migration inhibitory factor receptor complex

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of heterotypic cell-cell adhesion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

hyaluronan catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of regulatory T cell differentiation

1 reference

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of adaptive immune response

1 reference

14 February 2019

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of apoptotic process

NAS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of mature B cell apoptotic process

1 reference

14 February 2019

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

Wnt signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

cellular response to fibroblast growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

wound healing involved in inflammatory response

1 reference

14 February 2019

Resolution of lung inflammation by CD44

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

branching involved in prostate gland morphogenesis

1 reference

14 February 2019

Hyaluronan is a prerequisite for ductal branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of CD4-positive, alpha-beta T cell proliferation

1 reference

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

negative regulation of inflammatory response

1 reference

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of monocyte aggregation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

cytokine-mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of kinase activity

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

wound healing, spreading of cells

regulation of cell growth

ISS

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

24 April 2018

Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15379&geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

neuron projection development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of neutrophil apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

positive regulation of ERK1 and ERK2 cascade

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15379

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016