(Q21495400)

Rho GTPase activation protein

1 reference

Dbl homology (DH) domain superfamily

1 reference

Bcr-Abl oncoprotein oligomerisation domain superfamily

1 reference

Abr/Bcr

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

pleckstrin homology domain, protein family

1 reference

Bcr-Abl oncoprotein oligomerisation, protein family

1 reference

C2 domain, protein family

1 reference

Rho GTPase-activating protein domain family

1 reference

Dbl homology (DH) domain, protein family

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

GTPase activator activity

5 references

14 February 2019

Abnormal function of astroglia lacking Abr and Bcr RacGAPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

guanyl-nucleotide exchange factor activity

IDA

2 references

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

guanyl-nucleotide exchange factor activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

GTPase activator activity

7 references

9 May 2019

Abnormal function of astroglia lacking Abr and Bcr RacGAPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

IDA

postsynaptic membrane

1 reference

9 May 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

Schaffer collateral - CA1 synapse

1 reference

9 May 2019

Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

glutamatergic synapse

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

glutamatergic synapse

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

postsynaptic density, intracellular component

positive regulation of phagocytosis

1 reference

9 May 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

intracellular signal transduction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

neuromuscular process controlling balance

1 reference

9 May 2019

Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells

regulation of cell cycle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of blood vessel remodeling

IDA

1 reference

9 May 2019

Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

protein phosphorylation

1 reference

9 May 2019

negative regulation of cellular extravasation

1 reference

9 May 2019

Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

response to lipopolysaccharide

1 reference

9 May 2019

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

Abnormal function of astroglia lacking Abr and Bcr RacGAPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

regulation of vascular permeability

1 reference

9 May 2019

Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of cell migration

1 reference

9 May 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of neutrophil degranulation

1 reference

9 May 2019

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs

inner ear morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

regulation of Rho protein signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of inflammatory response

1 reference

9 May 2019

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

actin cytoskeleton organization

1 reference

9 May 2019

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

positive regulation of GTPase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

homeostasis of number of cells

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

regulation of nitrogen compound metabolic process

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

Increased neutrophil respiratory burst in bcr-null mutants

definitive hemopoiesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of respiratory burst

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

intracellular protein transmembrane transport

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

cellular response to lipopolysaccharide

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

negative regulation of reactive oxygen species metabolic process

1 reference

9 May 2019

Increased neutrophil respiratory burst in bcr-null mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

modulation of chemical synaptic transmission

1 reference

9 May 2019

Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PAJ1

regulation of Rho protein signal transduction

Rho GTPase-activating protein domain

1 reference

Bcr-Abl oncoprotein oligomerisation

1 reference

Dbl homology (DH) domain

1 reference

pleckstrin homology domain

1 reference

Guanine-nucleotide dissociation stimulator, CDC24, conserved site

1 reference

C2 domain

1 reference