(Q21495734)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05860

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Formin, FH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

27 March 2018

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05860&geneProductId=UniProtKB:Q05860

SH3 domain binding

1 reference

9 May 2019

Identification of a ten-amino acid proline-rich SH3 binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

actin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

14 February 2019

microtubule binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

14 February 2019

cell component

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

microtubule cytoskeleton

adherens junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

actin filament

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

3 references

14 February 2019

14 February 2019

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

14 February 2019

Genetic evidence that formins function within the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

3 references

9 May 2019

9 May 2019

Genetic evidence that formins function within the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

4 references

9 May 2019

9 May 2019

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

9 May 2019

Genetic evidence that formins function within the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

endoplasmic reticulum membrane

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

positive regulation of actin nucleation

biological process

1 reference

14 February 2019

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

dendrite morphogenesis

positive regulation of focal adhesion assembly

IGI

1 reference

9 May 2019

Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

forelimb morphogenesis

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

ureteric bud invasion

1 reference

9 May 2019

Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

actin nucleation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

9 May 2019

kidney development

1 reference

27 March 2018

The Role of a Single Formin Isoform in the Limb and Renal Phenotypes of Limb Deformity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05860&geneProductId=UniProtKB:Q05860

hindlimb morphogenesis

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

gene expression

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

skeletal system morphogenesis

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

positive regulation of actin filament polymerization

1 reference

9 May 2019

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

limb development

1 reference

9 May 2019

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

1 reference

InterPro Release 71.0