(Q21495734)

English

Formin 1

mammalian protein found in Mus musculus

formin-1
limb deformity protein
Fmn1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Formin homology family, Cappuccino subfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05860

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Formin, FH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

1 reference

27 March 2018

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05860&geneProductId=UniProtKB:Q05860

determination method

SH3 domain binding

determination method

1 reference

9 May 2019

Identification of a ten-amino acid proline-rich SH3 binding site

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

microtubule binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

adherens junction

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

plasma membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

14 February 2019

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

14 February 2019

Genetic evidence that formins function within the nucleus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

9 May 2019

Genetic evidence that formins function within the nucleus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

9 May 2019

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

9 May 2019

Genetic evidence that formins function within the nucleus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

endoplasmic reticulum membrane

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

biological process

positive regulation of actin nucleation

determination method

1 reference

14 February 2019

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

dendrite morphogenesis

determination method

positive regulation of focal adhesion assembly

determination method

1 reference

9 May 2019

Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

forelimb morphogenesis

determination method

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

ureteric bud invasion

determination method

1 reference

9 May 2019

Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

actin nucleation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

kidney development

determination method

1 reference

27 March 2018

The role of a single formin isoform in the limb and renal phenotypes of limb deformity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05860&geneProductId=UniProtKB:Q05860

determination method

hindlimb morphogenesis

determination method

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

gene expression

determination method

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

skeletal system morphogenesis

determination method

1 reference

9 May 2019

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

positive regulation of actin filament polymerization

determination method

1 reference

9 May 2019

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

limb development

determination method

1 reference

9 May 2019

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05860

determination method

Formin, FH2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q05860

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000080093

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000080093

ENSMUSP00000097171

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000097171

ENSMUSP00000099606

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000099606

ENSMUSP00000125052

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000125052

ENSMUSP00000159010

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000159010

PDB structure ID

1 reference

UniProt protein ID

22 March 2016

language of work or name

1 reference

UniProt protein ID

22 March 2016

language of work or name

1 reference

UniProt protein ID

22 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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