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(Q21495958)
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English
MAP-kinase activating death domain
mammalian protein found in Mus musculus
Madd
rab3 GDP/GTP exchange factor
Rab3 GEP
insulinoma-glucagonoma protein 20
MAP kinase-activating death domain protein
Rab3 GDP/GTP exchange protein
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q80U28
part of
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q80U28
encoded by
Madd
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q80U28
molecular function
guanyl-nucleotide exchange factor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IEA
cell component
integral component of membrane
determination method
ISS
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IEA
plasma membrane
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IEA
cytosol
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
nucleus
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
synaptic vesicle
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
synapse
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
axon cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IEA
biological process
regulation of apoptotic process
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
regulation of extrinsic apoptotic signaling pathway
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
execution phase of apoptosis
determination method
IMP
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
retrieved
14 February 2019
stated in
Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IMP
negative regulation of apoptotic signaling pathway
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IMP
regulation of Rab protein signal transduction
determination method
ISO
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U28&geneProductId=UniProtKB:Q80U28
determination method
ISO
regulation of cell cycle
determination method
IMP
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
retrieved
14 February 2019
stated in
Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IMP
apoptotic process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q80U28
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IEA
regulation of extrinsic apoptotic signaling pathway via death domain receptors
determination method
ISO
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U28&geneProductId=UniProtKB:Q80U28
determination method
ISO
negative regulation of growth hormone secretion
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
negative regulation of pancreatic amylase secretion
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
regulation of Rab protein signal transduction
determination method
IBA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IBA
anterograde synaptic vesicle transport
determination method
EXP
IDA
IMP
3 references
retrieved
14 February 2019
stated in
KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IMP
retrieved
14 February 2019
stated in
KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IDA
retrieved
14 February 2019
stated in
KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD.
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
EXP
regulation of extrinsic apoptotic signaling pathway via death domain receptors
determination method
IBA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
ISO
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U28
determination method
IBA
Identifiers
RefSeq protein ID
NP_001171190
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
NP_001171191
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
NP_663502
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106062
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106067
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106068
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106069
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106077
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106080
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106085
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106087
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106096
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106098
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106100
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106102
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106104
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106105
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106106
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106107
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106108
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106111
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106113
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_030106117
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017091
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017092
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017095
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017104
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017106
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017110
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017111
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017112
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017114
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017117
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017121
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017123
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017124
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017125
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017127
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017132
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017133
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017134
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017135
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017136
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017137
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017141
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017143
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017144
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017146
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017147
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017148
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
XP_036017150
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
228355
UniProt protein ID
Q80U28
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q80U28
Ensembl protein ID
ENSMUSP00000067210
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000067210
ENSMUSP00000069350
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000069350
ENSMUSP00000074746
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000074746
ENSMUSP00000077094
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000077094
ENSMUSP00000097311
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000097311
ENSMUSP00000097313
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000097313
ENSMUSP00000107000
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107000
ENSMUSP00000107001
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107001
ENSMUSP00000107002
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107002
ENSMUSP00000107003
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107003
ENSMUSP00000107004
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107004
ENSMUSP00000107006
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107006
ENSMUSP00000107007
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107007
ENSMUSP00000107012
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000107012
ENSMUSP00000117657
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000117657
Sitelinks
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(0 entries)
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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