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(Q21496070)
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Aph1 homolog B, gamma secretase subunit
mammalian protein found in Mus musculus
APH1B homolog
anterior pharynx defective 1c homolog
aph-1beta
Aph1b
APH-1b
anterior pharynx defective 1b homolog
gamma-secretase subunit APH-1B
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C7N7
part of
Gamma-secretase subunit Aph-1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8C7N7
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C7N7
encoded by
Aph1b
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C7N7
molecular function
endopeptidase activity
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8C7N7&geneProductId=UniProtKB:Q8C7N7
determination method
IGI
endopeptidase activity
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
cell component
integral component of membrane
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C7N7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
plasma membrane
determination method
TAS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
TAS
transport vesicle
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
ISO
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C7N7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
endoplasmic reticulum
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
integral component of plasma membrane
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
gamma-secretase complex
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
biological process
positive regulation of catalytic activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
protein processing
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
Notch signaling pathway
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C7N7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
Notch receptor processing
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C7N7
determination method
IBA
Identifiers
RefSeq protein ID
NP_808251
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
208117
XP_006510985
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
208117
UniProt protein ID
Q8C7N7
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C7N7
Ensembl protein ID
ENSMUSP00000034934
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000034934
ENSMUSP00000125816
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000125816
ENSMUSP00000109359
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000109359
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