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(Q21496081)
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GIT ArfGAP 1
mammalian protein found in Mus musculus
ARF GTPase-activating protein GIT1
ARF GAP GIT1
G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
G protein-coupled receptor kinase-interactor 1
Git1
GRK-interacting protein 1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q68FF6
part of
ARFGAP/RecO-like zinc finger
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
Ankyrin repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
ArfGAP domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Arf GTPase activating protein family
1 reference
based on heuristic
inferred from protein domain or family
Arf GTPase-activating protein GIT1/2, coiled-coil domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
GIT, Spa2 homology (SHD) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ankyrin repeat-containing domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
ARF GTPase-activating protein GIT1, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ankyrin repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q68FF6
encoded by
Git1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q68FF6
molecular function
protein binding
determination method
IPI
3 references
retrieved
14 February 2019
stated in
A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IPI
retrieved
14 February 2019
stated in
Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IPI
retrieved
14 February 2019
stated in
Proteomics analysis of immuno-precipitated synaptic protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IPI
metal ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q68FF6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
protein-containing complex binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IPI
GTPase activator activity
determination method
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q68FF6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
small GTPase binding
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
protein homodimerization activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
structural constituent of postsynaptic specialization
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
cell component
focal adhesion
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
cytoplasm
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q68FF6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
cytosol
determination method
IEA
ISO
TAS
3 references
retrieved
14 February 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
endosome
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
neuron projection
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
synapse
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
calyx of Held
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IMP
postsynapse
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
glutamatergic synapse
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
GABA-ergic synapse
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
biological process
dendritic spine development
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
regulation of cytokinesis
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
immunological synapse formation
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
positive regulation of GTPase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
ephrin receptor signaling pathway
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IDA
regulation of G protein-coupled receptor signaling pathway
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
negative regulation of ARF protein signal transduction
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
cellular response to epidermal growth factor stimulus
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
positive regulation of receptor catabolic process
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
maintenance of postsynaptic specialization structure
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IEA
presynaptic modulation of chemical synaptic transmission
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IMP
neurotransmitter receptor localization to postsynaptic specialization membrane
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
ISO
regulation of synaptic vesicle exocytosis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse
GOA
curator
SynGO
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q68FF6
determination method
IMP
has part(s)
ankyrin repeat-containing domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
Arf GTPase-activating protein GIT1/2, coiled-coil domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
GIT, Spa2 homology (SHD) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
ankyrin repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
ARF GTPase-activating protein GIT1, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
Arf GTPase activating protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q68FF6
Identifiers
RefSeq protein ID
NP_001004144
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
216963
NP_001361687
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
216963
UniProt protein ID
Q68FF6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q68FF6
Ensembl protein ID
ENSMUSP00000037210
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000037210
ENSMUSP00000098375
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000098375
Sitelinks
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Wikiquote
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Multilingual sites
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