(Q21497009)

Neutral ceramidase, C-terminal domain superfamily

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

Neutral/alkaline non-lysosomal ceramidase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Neutral/alkaline non-lysosomal ceramidase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

12 September 2018

1 reference

12 September 2018

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

N-acylsphingosine amidohydrolase activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 January 2018

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

N-acylsphingosine amidohydrolase activity

IPI

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

phytoceramidase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

dihydroceramidase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

phytoceramidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

dihydroceramidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

integral component of membrane

cell component

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

4 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

14 January 2019

Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

2 references

extracellular exosome

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

cell population proliferation

IDA

extracellular exosome

1 reference

1 January 2018

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

sphingolipid metabolic process

TAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

response to organic substance

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

long-chain fatty acid biosynthetic process

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

regulation of mitotic cell cycle

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

1 reference

9 May 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

IMP

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

5 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

ceramide biosynthetic process

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

5 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

negative regulation of apoptotic signaling pathway

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHE3&geneProductId=UniProtKB:Q9JHE3

ISS

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

ceramide biosynthetic process

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

cellular response to cytokine stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

response to organic substance

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

ceramide biosynthetic process

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

9 May 2019

Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

IMP

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

8 April 2019

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

8 April 2019

Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

8 April 2019

Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHE3

Neutral/alkaline non-lysosomal ceramidase, N-terminal

has part(s)

1 reference

Neutral/alkaline non-lysosomal ceramidase, C-terminal

1 reference