(Q21497166)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Interactions in the network of Usher syndrome type 1 proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

protein N-terminus binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

integral component of membrane

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

1 reference

14 February 2019

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

1 reference

14 February 2019

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

2 references

photoreceptor inner segment

1 reference

14 February 2019

Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

2 references

3 references

14 February 2019

Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

cochlear hair cell ribbon synapse

1 reference

14 February 2019

Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

photoreceptor ribbon synapse

IDA

1 reference

14 February 2019

Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

IDA

biological process

1 reference

14 February 2019

Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

regulation of cytosolic calcium ion concentration

ISS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

4 references

14 February 2019

Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Chromosomal localization of a gene responsible for vestibulocochlear defects of BUS/Idr mice: identification as an allele of waltzer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

post-embryonic animal organ morphogenesis

IEA

1 reference

14 February 2019

The anatomy and development of the mutants pirouette, shaker-1 and waltzer in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

15 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

A major gene affecting age-related hearing loss in C57BL/6J mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Chromosomal localization of a gene responsible for vestibulocochlear defects of BUS/Idr mice: identification as an allele of waltzer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

The effect of an age-related hearing loss gene (Ahl) on noise-induced hearing loss and cochlear damage from low-frequency noise

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

A point mutation in a cadherin gene, Cdh23, causes deafness in a novel mutant, Waltzer mouse niigata

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

The anatomy and development of the mutants pirouette, shaker-1 and waltzer in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

auditory receptor cell stereocilium organization

IEA

9 references

14 February 2019

Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Vestibulocochlear Defects and Effects of Deuterium Oxide in Mutant Bustling (BUS) Mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

A point mutation in a cadherin gene, Cdh23, causes deafness in a novel mutant, Waltzer mouse niigata

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Cochlear histopathology of the mutant bustling mouse, BUS/Idr

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Degenerative hairlets on the vestibular sensory cells in mutant bustling (BUS/Idr) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

inner ear auditory receptor cell differentiation

IGI

1 reference

14 February 2019

Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

3 references

14 February 2019

Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

inner ear development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

Cochlear histopathology of the mutant bustling mouse, BUS/Idr

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

14 February 2019

The anatomy and development of the mutants pirouette, shaker-1 and waltzer in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

photoreceptor cell maintenance

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

calcium ion transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

homophilic cell adhesion via plasma membrane adhesion molecules

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99PF4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99PF4

Cadherin conserved site

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99PF4

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016