(Q21498638)

http://www.ebi.ac.uk/interpro/protein/Q8BGI3

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

1 reference

25 May 2022

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

endoplasmic reticulum membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

endoplasmic reticulum

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

roof of mouth development

biological process

1 reference

14 February 2019

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

steroid metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

negative regulation of fat cell differentiation

1 reference

14 February 2019

Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

sterol biosynthetic process

IDA

1 reference

14 February 2019

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

negative regulation of fatty acid biosynthetic process

1 reference

14 February 2019

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

cholesterol metabolic process

3 references

14 February 2019

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

response to sterol depletion

1 reference

14 February 2019

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

cranial suture morphogenesis

IDA

1 reference

14 February 2019

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

inner ear morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

middle ear morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

cholesterol biosynthetic process

1 reference

14 February 2019

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

triglyceride metabolic process

1 reference

14 February 2019

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3

negative regulation of steroid biosynthetic process

1 reference

14 February 2019

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BGI3