(Q21498660)

English

Integrin alpha 6

mammalian protein found in Mus musculus

VLA-6
integrin alpha-6
Itga6
CD49 antigen-like family member F

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

Integrin domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

integrin alpha chain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

Integrin alpha, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Integrin alpha beta-propellor, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha-2, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha chain, C-terminal cytoplasmic region, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

integrin binding

determination method

1 reference

16 July 2018

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61739&geneProductId=UniProtKB:Q61739

determination method

insulin-like growth factor I binding

determination method

neuregulin binding

determination method

protein binding

determination method

5 references

8 April 2019

Requirement of CD9 on the egg plasma membrane for fertilization.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Meltrin gamma(ADAM-9) mediates cellular adhesion through alpha(6)beta(1 )integrin, leading to a marked induction of fibroblast cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Tetraspanin CD151 promotes cell migration by regulating integrin trafficking

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Peripheral myelin protein 22 is in complex with alpha6beta4 integrin, and its absence alters the Schwann cell basal lamina.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

cadherin binding

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61739&geneProductId=UniProtKB:Q61739

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

basal part of cell

determination method

1 reference

8 April 2019

Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

plasma membrane

determination method

8 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

The tetraspan protein epithelial membrane protein-2 interacts with beta1 integrins and regulates adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Distribution of alpha 6 integrin subunit in developing mouse submandibular gland

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Differential expression of alpha 3 and alpha 6 integrins in the developing mouse inner ear

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

determination method

1 reference

8 April 2019

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

basement membrane

determination method

1 reference

8 April 2019

Distribution of dystroglycan in normal adult mouse tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

determination method

3 references

basal plasma membrane

determination method

basolateral plasma membrane

determination method

1 reference

8 April 2019

Differential expression of alpha 3 and alpha 6 integrins in the developing mouse inner ear

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

external side of plasma membrane

determination method

4 references

8 April 2019

A putative role for microRNA-205 in mammary epithelial cell progenitors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

8 April 2019

The L1 adhesion molecule is a cellular ligand for VLA-5

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

biological process

cellular response to extracellular stimulus

determination method

1 reference

8 April 2019

Screen for genes regulated during early kidney morphogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

positive regulation of cell-cell adhesion

determination method

1 reference

8 April 2019

Adhesive hierarchy involving the cell adhesion molecules L1, CD24, and alpha 6 integrin in murine neuroblastoma N2A cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

filopodium assembly

determination method

1 reference

8 April 2019

Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

odontogenesis of dentin-containing tooth

determination method

1 reference

8 April 2019

Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

cell adhesion mediated by integrin

determination method

1 reference

16 July 2018

The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61739&geneProductId=UniProtKB:Q61739

determination method

brown fat cell differentiation

determination method

1 reference

8 April 2019

Wdnm1-like, a new adipokine with a role in MMP-2 activation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

integrin-mediated signaling pathway

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

cell-matrix adhesion

determination method

1 reference

8 April 2019

Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

ectodermal cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

cellular response to organic cyclic compound

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

positive regulation of neuron projection development

determination method

1 reference

8 April 2019

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61739

determination method

Integrin alpha chain, C-terminal cytoplasmic region, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

Integrin alpha-2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

Integrin alpha beta-propellor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61739

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

15 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000028522

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000028522

ENSMUSP00000107729

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000107729

ENSMUSP00000118086

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118086

ENSMUSP00000158895

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000158895

Sitelinks

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Multilingual sites(0 entries)

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