(Q21498768)

http://www.ebi.ac.uk/interpro/protein/Q8CBW3

Abl interactor 1

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8CBW3

membrane protein

1 reference

inferred from GOA cell component → membrane

Target SNARE coiled-coil homology domain, protein family

1 reference

Abl Interactor 1, SH3 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Abl-interactor, homeo-domain homologous domain, protein family

1 reference

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

1 reference

25 May 2022

1 reference

25 May 2022

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

The schizophrenia susceptibility gene dysbindin regulates dendritic spine dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

transcription factor binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

9 references

10 September 2018

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

The schizophrenia susceptibility gene dysbindin regulates dendritic spine dynamics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

3 references

protein tyrosine kinase activator activity

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

protein-containing complex binding

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

protein-containing complex binding

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

IEA

postsynaptic membrane

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

4 references

24 April 2018

NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

24 April 2018

Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

2 references

5 references

14 February 2019

NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CBW3&geneProductId=UniProtKB:Q8CBW3

glutamatergic synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

1 reference

14 February 2019

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

megakaryocyte development

1 reference

14 February 2019

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

lamellipodium morphogenesis

1 reference

14 February 2019

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

positive regulation of protein tyrosine kinase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

The schizophrenia susceptibility gene dysbindin regulates dendritic spine dynamics

IEA

dendrite morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

actin polymerization or depolymerization

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3

megakaryocyte development

IEA

lamellipodium morphogenesis

postsynapse to nucleus signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CBW3