(Q21499140)

beta-1,4-galactosyltransferase

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

galactosyltransferase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

galactosyltransferase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

N-acetyllactosamine synthase activity

galactosyltransferase activity

IEA

ISO

3 references

1 reference

14 February 2019

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

lactose synthase activity

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

manganese ion binding

3 references

glycosyltransferase activity

beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity

IEA

2 references

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Targeted mutation in beta1,4-galactosyltransferase leads to pituitary insufficiency and neonatal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Presence of polysialic acid and HNK-1 carbohydrate on brain glycoproteins from beta-1,4-galactosyltransferase-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Impaired galactosylation of core 2 O-glycans in erythrocytes of beta1,4-galactosyltransferase knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Enhanced branching morphogenesis in mammary glands of mice lacking cell surface beta1,4-galactosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Expression of beta1,4-galactosyltransferase in the development of mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

protein homodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

ISO

alpha-tubulin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

ISO

protein kinase binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

6 references

31 January 2018

Mammary gland morphogenesis is inhibited in transgenic mice that overexpress cell surface beta1,4-galactosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

31 January 2018

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

31 January 2018

Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

31 January 2018

Overexpressing sperm surface beta 1,4-galactosyltransferase in transgenic mice affects multiple aspects of sperm-egg interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

31 January 2018

Molecular analysis of cell surface beta-1,4-galactosyltransferase function during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Cell surface and Golgi pools of beta-1,4-galactosyltransferase are differentially regulated during embryonal carcinoma cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Cell surface and Golgi pools of beta-1,4-galactosyltransferase are differentially regulated during embryonal carcinoma cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

Golgi cisterna membrane

1 reference

14 February 2019

1 reference

31 January 2018

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

epithelial cell development

HDA

biological process

1 reference

14 February 2019

Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

glycoprotein biosynthetic process

4 references

14 February 2019

Impaired galactosylation of core 2 O-glycans in erythrocytes of beta1,4-galactosyltransferase knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Knockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Polylactosamine synthesis and branch formation of N-glycans in beta1,4-galactosyltransferase-1-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

mammary gland development

1 reference

31 January 2018

Enhanced branching morphogenesis in mammary glands of mice lacking cell surface beta1,4-galactosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

negative regulation of cell population proliferation

IGI

angiogenesis involved in wound healing

2 references

1 reference

14 February 2019

Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

regulation of acrosome reaction

1 reference

14 February 2019

Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

positive regulation of epithelial cell proliferation involved in wound healing

1 reference

14 February 2019

Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

extracellular matrix organization

1 reference

14 February 2019

Enhanced branching morphogenesis in mammary glands of mice lacking cell surface beta1,4-galactosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

positive regulation of apoptotic process involved in mammary gland involution

1 reference

31 January 2018

Apoptosis and involution in the mammary gland are altered in mice lacking a novel receptor, beta1,4-Galactosyltransferase I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

development of secondary sexual characteristics

1 reference

14 February 2019

Enhanced branching morphogenesis in mammary glands of mice lacking cell surface beta1,4-galactosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

galactose metabolic process

1 reference

14 February 2019

Expression of beta1,4-galactosyltransferase in the development of mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

acute inflammatory response

IGI

1 reference

14 February 2019

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

lactose biosynthetic process

1 reference

14 February 2019

Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

branching morphogenesis of an epithelial tube

penetration of zona pellucida

1 reference

14 February 2019

Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

1 reference

14 February 2019

Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

oligosaccharide biosynthetic process

regulation of cell population proliferation

1 reference

31 January 2018

Altering the Expression of Cell Surface β1,4-Galactosyltransferase Modulates Cell Growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15535&geneProductId=UniProtKB:P15535

binding of sperm to zona pellucida

3 references

14 February 2019

Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Overexpressing sperm surface beta 1,4-galactosyltransferase in transgenic mice affects multiple aspects of sperm-egg interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

14 February 2019

Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

positive regulation of apoptotic process

1 reference

14 February 2019

Apoptosis and involution in the mammary gland are altered in mice lacking a novel receptor, beta1,4-Galactosyltransferase I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

protein N-linked glycosylation

3 references

carbohydrate metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

negative regulation of cell population proliferation

IEA

1 reference

14 February 2019

Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15535

galactosyltransferase, N-terminal

has part(s)

1 reference

galactosyltransferase, C-terminal

1 reference