(Q21499172)

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Ambra1 regulates autophagy and development of the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Endogenous HMGB1 regulates autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

protein homodimerization activity

IPI

1 reference

8 April 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

mitochondrial membranes

1 reference

8 April 2019

phosphatidylinositol 3-kinase complex, class III

1 reference

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

phagophore assembly site

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

phosphatidylinositol 3-kinase complex, class III, type I

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

endoplasmic reticulum

1 reference

8 April 2019

1 reference

8 April 2019

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

phosphatidylinositol 3-kinase complex, class III, type II

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

protein-containing complex

1 reference

8 April 2019

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Ambra1 regulates autophagy and development of the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

extrinsic component of membrane

cellular response to glucose starvation

1 reference

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

2 references

engulfment of apoptotic cell

1 reference

8 April 2019

Involvement of Beclin 1 in engulfment of apoptotic cells

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

late endosome to vacuole transport

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cytoplasm to vacuole transport by the Cvt pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to aluminum ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

amyloid-beta metabolic process

1 reference

8 April 2019

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

response to vitamin E

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to epidermal growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

response to other organism

1 reference

8 April 2019

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

defense response to virus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

negative regulation of reactive oxygen species metabolic process

1 reference

8 April 2019

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88597&geneProductId=UniProtKB:O88597

regulation of catalytic activity

1 reference

8 April 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

lysosome organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

negative regulation of cell population proliferation

1 reference

8 April 2019

Ambra1 regulates autophagy and development of the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to nitrogen starvation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

3 references

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

response to iron(II) ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

response to nutrient levels

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to amino acid starvation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to hydrogen peroxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

cellular response to copper ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

autophagy of mitochondrion

3 references

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Ambra1 regulates autophagy and development of the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Identification of a candidate therapeutic autophagy-inducing peptide

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

early endosome to late endosome transport

negative regulation of autophagy

1 reference

8 April 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

positive regulation of cardiac muscle hypertrophy

1 reference

8 April 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

negative regulation of autophagosome assembly

1 reference

8 April 2019

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

regulation of cytokinesis

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

autophagosome assembly

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88597&geneProductId=UniProtKB:O88597

24 April 2018

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88597&geneProductId=UniProtKB:O88597

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88597&geneProductId=UniProtKB:O88597

negative regulation of apoptotic process

3 references

autophagosome assembly

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88597