(Q21499359)

GPCR, family 2, corticotropin releasing factor receptor, type 2

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

GPCR, family 2, extracellular hormone receptor domain, protein family

1 reference

inferred from protein domain or family

GPCR, family 2-like

1 reference

inferred from protein domain or family

GPCR, family 2, secretin-like, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

G protein-coupled receptor activity

2 references

1 reference

14 February 2019

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

corticotrophin-releasing factor receptor activity

IPI

transmembrane signaling receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

peptide hormone binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

corticotropin-releasing hormone receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

corticotrophin-releasing factor receptor activity

3 references

14 February 2019

Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

14 February 2019

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

integral component of membrane

IBA

cell component

2 references

2 references

1 reference

24 April 2018

A novel corticotropin-releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress-induced heart disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

A novel corticotropin-releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress-induced heart disease

endoplasmic reticulum

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

rough endoplasmic reticulum

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

2 references

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

G protein-coupled receptor signaling pathway

biological process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

14 February 2019

Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of cAMP-mediated signaling

1 reference

24 April 2018

A novel corticotropin-releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress-induced heart disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

cell surface receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of angiogenesis

1 reference

14 February 2019

Corticotropin-releasing factor receptor 2 is a tonic suppressor of vascularization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

cellular response to corticotropin-releasing hormone stimulus

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

actin filament organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

protein kinase C-activating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

hormone-mediated signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of heart rate

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of norepinephrine secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of serotonin secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

sensory perception of pain

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

epithelial cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of interleukin-6 production

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of epinephrine secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of stress-activated MAPK cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of luteinizing hormone secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

catecholamine biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of blood pressure

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of follicle-stimulating hormone secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

skeletal muscle tissue growth

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of NF-kappaB transcription factor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

long-term potentiation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60748&geneProductId=UniProtKB:Q60748

negative regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of calcium ion import

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of feeding behavior

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

negative regulation of defecation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of cAMP-mediated signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

positive regulation of DNA biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60748

1 reference

GPCR, family 2, secretin-like, conserved site

1 reference

GPCR, family 2, extracellular hormone receptor domain

1 reference