(Q21499451)

English

Adducin 1 (alpha)

mammalian protein found in Mus musculus

Add1
alpha-adducin
erythrocyte adducin subunit alpha

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYC0

Class II aldolase/adducin N-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYC0

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Class II aldolase/adducin N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

structural molecule activity

determination method

1 reference

24 April 2018

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

calmodulin binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

T cell receptor binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

cadherin binding

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

spectrin binding

determination method

3 references

actin filament binding

determination method

3 references

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

3 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

3 references

plasma membrane

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Adducin is involved in endothelial barrier stabilization

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

postsynaptic density

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

dendritic spine

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

perinuclear region of cytoplasm

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

plasma membrane raft

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

biological process

cell volume homeostasis

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

multicellular organism growth

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

in utero embryonic development

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

cell morphogenesis

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

erythrocyte differentiation

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

homeostasis of number of cells within a tissue

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

hemoglobin metabolic process

determination method

1 reference

14 February 2019

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

cellular response to calcium ion

determination method

3 references

positive regulation of establishment of endothelial barrier

determination method

3 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

Adducin is involved in endothelial barrier stabilization

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

positive regulation of adherens junction organization

determination method

3 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

Adducin is involved in endothelial barrier stabilization

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QYC0&geneProductId=UniProtKB:Q9QYC0

determination method

negative regulation of actin filament polymerization

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

positive regulation of angiogenesis

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

positive regulation of endocytosis

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

cellular response to retinoic acid

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

barbed-end actin filament capping

determination method

3 references

actin filament bundle assembly

determination method

3 references

positive regulation of establishment of endothelial barrier

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Adducin is involved in endothelial barrier stabilization

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

positive regulation of adherens junction organization

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Adducin is involved in endothelial barrier stabilization

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QYC0

determination method

Class II aldolase/adducin N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QYC0

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

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20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000109977

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109977

ENSMUSP00000109979

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109979

ENSMUSP00000001108

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000001108

ENSMUSP00000052266

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000052266

ENSMUSP00000109974

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000109974

ENSMUSP00000114984

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000114984

ENSMUSP00000116075

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000116075

ENSMUSP00000118539

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118539

ENSMUSP00000121402

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121402

ENSMUSP00000144673

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000144673

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