(Q21980349)

Calpain large subunit, domain III superfamily

1 reference

EF-hand domain pair

1 reference

Papain-like cysteine peptidase superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

EF-hand domain, protein family

1 reference

Peptidase C2, calpain, large subunit, domain III, protein family

1 reference

Peptidase C2, calpain, domain III, protein family

1 reference

Calpain subdomain III, protein family

1 reference

Peptidase C2, calpain, catalytic domain, protein family

1 reference

Cysteine peptidase, cysteine active site, protein family

1 reference

EF-Hand 1, calcium-binding site, protein family

1 reference

cysteine-type peptidase activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

calcium-dependent cysteine-type endopeptidase activity

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

calcium-dependent cysteine-type endopeptidase activity

7 references

14 February 2019

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

4 references

14 February 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

1 reference

14 February 2019

Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

14 February 2019

Calpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

10 September 2018

Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

mitochondrial outer membrane

IBA

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

mitochondrial intermembrane space

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

external side of plasma membrane

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

regulation of cytoskeleton organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

m-Calpain is required for preimplantation embryonic development in mice.

blastocyst development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

24 April 2018

Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

cellular response to amino acid stimulus

IDA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

positive regulation of cardiac muscle cell apoptotic process

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

regulation of interleukin-6 production

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

cellular response to interferon-beta

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

response to hydrogen peroxide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

behavioral response to pain

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

cellular response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08529

positive regulation of neuron death

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

positive regulation of myoblast fusion

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

positive regulation of phosphatidylcholine biosynthetic process

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08529&geneProductId=UniProtKB:O08529

Peptidase C2, calpain, catalytic domain

has part(s)

1 reference

Peptidase C2, calpain, large subunit, domain III

1 reference

EF-hand 1, calcium-binding site

1 reference

Peptidase C2, calpain, domain III

1 reference

EF-hand domain

1 reference

Cysteine peptidase, cysteine active site

1 reference

Calpain subdomain III

1 reference