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(Q21981115)
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G protein-coupled receptor 6
mammalian protein found in Mus musculus
G-protein coupled receptor 6
sphingosine 1-phosphate receptor GPR6
Gpr6
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q6YNI2
part of
G protein-coupled receptor 6
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6YNI2
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q6YNI2
encoded by
Gpr6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q6YNI2
molecular function
sphingosine-1-phosphate receptor activity
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IDA
G protein-coupled receptor activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
signal transducer activity
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6YNI2&geneProductId=UniProtKB:Q6YNI2
determination method
IEA
cell component
integral component of membrane
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
biological process
positive regulation of cytosolic calcium ion concentration
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IDA
G protein-coupled receptor signaling pathway
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
signal transduction
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6YNI2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
sphingosine-1-phosphate receptor signaling pathway
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6YNI2
determination method
IEA
physically interacts with
sphingosine 1-phosphate
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
911
language of work or name
English
retrieved
17 August 2016
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q6YNI2
Identifiers
RefSeq protein ID
NP_951013
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
140741
UniProt protein ID
Q6YNI2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q6YNI2
Ensembl protein ID
ENSMUSP00000057323
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000057323
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